Capsaicin effects on blinking

Arquivos de Neuro-Psiquiatria

Fidias E. Leon-sarmiento²  Jaime Bayona-prieto²  Marta E. Leon-s¹ 

[1] ,Universidad de Pamplona Facultad de Salud Instituto de Neurología Clínica y Funcional, Neurociencias Aplicadas & Neurobiología HumanaPamplona,Colombia

关键词: capsaicin;    visuomotor integration;    C-fibers;    blinking;    dystonia;    capsaicina;    integración visuomotora;    fibras C;    parpadeo;    distonía;   

DOI  :  10.1590/S0004-282X2005000500004

来源: SciELO

【 摘 要 】

Blinking is a normal human phenomenom involving trigeminal and facial patways. To gain understanding on the neurobiology of blinking, five normal subjects were investigated before and after application of transdermal capsaicin at the forehead for two weeks. No effects of topical capsaicin were detected in eye blink rates. However, when capsaicin was applied to a female subject with blepharospasm, she showed a dramatic restoration of her vision subsequent to blinking modification. Deactivation of abnormal A-to-C fibers cross talks at the trigeminal-facial pathways seems to be the most likely mechanism of such improvement.

【 授权许可】

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