Botulinum toxin for treatment of cocontractions related to obstetrical brachial plexopathy

Arquivos de Neuro-Psiquiatria

Carlos O. Heise¹  Lilian R. Gonçalves¹  Egberto R. Barbosa¹  Jose Luiz D. Gherpelli¹ 

[1] ,University of São Paulo Medical School Department of Neurology São Paulo SP ,Brazil

关键词: botulinum toxin type A;    obstetric paralysis;    drug therapy;    toxina botulínica tipo A;    paralisia obstétrica;    terapia por drogas;   

DOI  :  10.1590/S0004-282X2005000400006

来源: SciELO

【 摘 要 】

Botulinum toxin type A was recently introduced for treatment of biceps - triceps muscle cocontraction, which compromises elbow function in children with obstetrical brachial plexopathy. This is our preliminary experience with this new approach. Eight children were treated with 2 - 3 U/kg of botulinum toxin injected in the triceps (4 patients) and biceps (4 patients) muscle, divided in 2 or 3 sites. All patients submitted to triceps injections showed a long-lasting improvement of active elbow flexion and none required new injections, after a follow-up of 3 to 18 months. Three of the patients submitted to biceps injections showed some improvement of elbow extension, but none developed anti-gravitational strength for elbow extension and the effect lasted only three to five months. One patient showed no response to triceps injections. Our data suggest that botulinum toxin can be useful in some children that have persistent disability secondary to obstetrical brachial plexopathy.

【 授权许可】

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