Cerebral tuberculomas in AIDS patients: a forgotten diagnosis?

Arquivos de Neuro-Psiquiatria

José E. Vidal²  Adrián V. Hernández¹  Augusto C. Penalva De Oliveira¹  Alexandre De Leite Souza²  Geraldine Madalosso²  Paula R. Marques Da Silva²  R. Dauar¹ 

[1] ,Institute of Infectious Disease Emilio Ribas Departments of Infectology Sao Paulo SP ,Brazil

关键词: tuberculoma;    tuberculosis;    central nervous system;    acquired immunodeficiency syndrome;    tuberculoma;    tuberculose;    sistema nervoso central;    sindrome da imunodeficiência adquirida;   

DOI  :  10.1590/S0004-282X2004000500010

来源: SciELO

【 摘 要 】

The human immunodeficiency virus (HIV) infection epidemics increased the prevalence, multi-drug resistance and disseminated forms of tuberculosis. The central nervous system (CNS) tuberculosis has high mortality and morbidity, and it is usually divided into diffuse (meningitis) and localized (tuberculoma and abscess) forms. We report three cases of cerebral tuberculomas in AIDS patients: one with definitive diagnosis, confirmed with histopathology, and two with probable diagnosis, based on clinical information, radiological images, Mycobaterium tuberculosis isolation out of the CNS and adequate response to antituberculous treatment. Further, we discuss diagnostic, therapeutic and prognostic issues of tuberculomas, with emphasis in the distinction from cerebral tuberculous abscesses. Despite of their infrequent presentation, tuberculomas should be considered in the differential diagnosis of cerebral expansive lesions in patients with AIDS.

【 授权许可】

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