Hypertrophic pachymeningitis: case report

Arquivos de Neuro-Psiquiatria

Leonardo De Deus-silva²  Luciano De Souza Queiroz¹  Verônica De Araújo Zanardi¹  Enrico Ghizoni²  Hoyama Da Costa Pereira²  George Linard Silva Malveira²  Clodoaldo Pirani Jr²  Benito Pereira Damasceno¹  Fernando Cendes¹ 

[1] ,University of CampinasCampinas SP ,Brazil

关键词: hypertrophic pachymeningits;    neurosarcoidosis;    psychosis;    optic neuropathy;    paquimeningite hipertrófica;    neurossarcoidose;    psicose;    neuropatia óptica;   

DOI  :  10.1590/S0004-282X2003000100021

来源: SciELO

【 摘 要 】

Hypertrophic pachymeningits is an unusual cause of neurological symptoms and is often secondary to infections, carcinomatosis or inflammatory diseases. It may also be idiopathic. We report a case of pachymeningitis which was manifested primarily by psychosis and visual loss with optic atrophy and destruction of nasal septum. The patient, a 45 year old woman was submitted to extensive investigation without evidence of any underlying disease. A meningeal biopsy was performed and showed a mostly unspecific inflammatory process with extensive fibrosis of the dura and few early stage granulomas. These findings suggest either neurosarcoidosis or idiopathic hypertrophic pachymeningitis.

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