Pineal metastasis as first clinical manifestation of colorectal adenocarcinoma: case report

Arquivos de Neuro-Psiquiatria

Ricardo Ramina²  MaurÍcio Coelho Neto¹  Wagner M. Mariushi¹  Walter O. Arruda¹ 

[1] ,Curitiba Skull Base Foundation Hospital das Nações Curitiba,Brazil

关键词: pineal tumors;    cerebral metastases;    colorectal adenocarcinoma;    tumores da pineal;    metástases cerebrais;    adenocarcinoma colorretal;   

DOI  :  10.1590/S0004-282X1999000100018

来源: SciELO

【 摘 要 】

Cerebral metastases from colorectal adenocarcinomas occur in 8% of the cases. Diagnosis is usually made when primary disease and widespread metastases are already known. We report the case of a patient with single metastases in the pineal region as the first clinical manifestation of a colorectal adenocarcinoma. A 48-year-old female with Parinaud's syndrome for 15 days prior her admission was evaluated in our clinic. She had no symptoms or signs of colorectal disease. MRI examination revealed an heterogeneous lesion with peritumoral gadolinium enhancement, located in the pineal region. The tumor was radically resected through an infratentorial/supracerebellar approach. Histology showed metastatic carcinoma and immunohistochemical examination showed gastrointestinal tract adenocarcinoma. Metastases to the pineal region are extremely rare and should be considered in the differential diagnosis of tumors of this region.

【 授权许可】

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