Pulmonary involvement in patients with HTLV-I associated myelopathy

Arquivos de Neuro-Psiquiatria

Kilma Mattos¹  Ailton Melo¹  Conceição Queiroz Leandro Publio¹  Antonio Carlos Peçanha-martins¹  Virgínia Freitas¹  Irenio Gomes¹ 

[1] ,Federal University of Bahia

关键词: HTLV-I;    TSP;    encephalomyeloneuropathy;    myelopathy;    HTLV-I associated myelopathy (HAM);    alveolitis;    HTLV-I;    TSP;    encefalomieloneuropatia;    mielopatia;    HAM;    alveolites;   

DOI  :  10.1590/S0004-282X1995000500009

来源: SciELO

【 摘 要 】

Pulmonary involvement in HTLV-I patients has been identified by several authors in Africa, Japan and Brazil. The objective of this controlled study is to establish an association between HAM and lymphocytosis in the bronchoalveolar fluid (BAL). Thirty-five adult patients with non-traumatic and non-tumoral myelopathy filled out a detailed historical survey and underwent a neurological examination, a thoracic radiological evaluation and a CSF examination. Of the patients in this sample, 22 were diagnosed with HTLV-I associated myelopathy and 13 had myelopathies with other etiologies. Lymphocytosis in the BAL fluid was detected in 18 (82%) of the HAM patients and in 2 (15%) of non-HAM patients. We concluded that the lung represents an important organ in the pathogenesis of HAM.

【 授权许可】

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