Multiple sclerosis and positive lyme serology

Arquivos de Neuro-Psiquiatria

Marco Aurélio Lana-peixoto¹ 

[1] ,Universidade Federal de Minas Gerais Faculdade de Medicina

关键词: Lyme disease;    Lyme neuroborreliosis;    multiple sclerosis;    positive serology;    doença de Lyme;    neuroborreliose;    esclerose múltipla;    serologia positiva;   

DOI  :  10.1590/S0004-282X1994000400019

来源: SciELO

【 摘 要 】

As Lyme neuroborreliosis (LNB) may clinically mimick multiple sclerosis (MS) the presence of antibodies to Borrelia burgdorferi in serum of patients with a MS-like disease in non-edemic areas for Lyme disease may be troublesome. We report the case of a 45-year-old white female with the diagnosis of relapsing/ remitting form of MS due to a 15-year history of optic neuritis and recurrent episodes of motor and sensation disturbance in the upper right limb and in both lower extremites associated with bladder dysfunction. A magnetic resonance imaging of the brain revealed multiple high intensity periventricular white matter lesions. The patient had been exposed to ticks but did not recall the presence of erythema migrans. ELISA for Lyme disease was positive in two different laboratories and the positive serology was confirmed by Western blotting. No convincing reponse followed treatment with ceftriaxone. Although it is clear that the patient had been infect by Borrelia burgdorferi the relationship of this spirochetal infection with the neurological disease could not be ascertained.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License