Drastic effect of ranibizumab on choroidal neovascularization in idiopathic angioid streaks

Arquivos Brasileiros de Oftalmologia

Umit Yolcu¹  Fatih C. Gundogan¹  Oktay Diner¹ 

关键词: Angioid streaks;    Antibodies;    monoclonal/therapeutic use;    Antibodies;    monoclonal/drug effects;    Antibodies;    monoclonal;    humanized/drug effects;    Choroidal neovascularization/drug therapy;    Case reports;    Estrias angióides;    Anticorpos monoclonais/uso terapêutico;    Anticorpos monoclonais/efeitos de drogas;    Anticorpos monoclonais humanizados/efeito de drogas;    Neovascularização de coroide/efeito de drogas;    Relatos de casos;   

DOI  :  10.5935/0004-2749.20150067

来源: SciELO

【 摘 要 】

ABSTRACTA 28-year-old man presented with bilateral vision loss. His best-corrected visual acuity (BCVA) was 0.3 in the right eye (OD) and 0.6 in the left eye (OS). Fundoscopy and fluorescein angiography showed angioid streaks encircling the optic discs of both eyes (OU). Spectral Domain Optical Coherence Tomography (SD-OCT) showed bilateral macular serous detachment. Systemic and ocular screening tests showed no specific cause for the angioid streaks. The patient had previously received pegaptanib sodium injection on three occasions, photodynamic therapy in OS, and no treatment in OD. Upon intravitreal injection of ranibizumab (twice in OU), subretinal fluid was nearly eliminated in OU. BCVA increased to 0.6 in OD and 0.9 in OS, and remained improved until 6 months after treatment.

【 授权许可】

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