Proliferative sickle cell retinopathy associated with sickle cell trait and gestational diabetes: case report

Arquivos Brasileiros de Oftalmologia

Jefferson Augusto Santana Ribeiro²  Daniel Da Rocha Lucena¹  Levy Da Rocha Lucena¹  Rodrigo Jorge¹ 

[1] ,Universidade de São Paulo School of Medicine of Ribeirão Preto Ribeirão Preto SP ,Brazil

关键词: Sickle cell trait;    Retinal neovascularization;    Retinal detachment;    Gestational diabetes;    Hypertension;    pregnancy-induced;    Traço falciforme;    Neovascularização retiniana;    Descolamento de retina;    Diabetes gestacional;    Hipertensão induzida pela gravidez;   

DOI  :  10.1590/S0004-27492009000300025

来源: SciELO

【 摘 要 】

Proliferative sickle cell retinopathy is an uncommon complication in individuals with sickle cell trait (AS). However, the risk for proliferative retinopathy development is increased in patients with AS hemoglobinopathy associated with systemic conditions or ocular trauma. A case of a patient with AS hemoglobinopathy who developed proliferative sickle cell retinopathy after the occurrence of gestational diabetes and pregnancy-induced hypertension is reported. Hemoglobin electrophoresis revealed presence of A2 5.0%, S 35.0% and A 53.2%. The present case emphasizes the importance of evaluating systemic comorbidities in patients with sickle cell trait during pregnancy since sickle cell retinopathy can progress rapidly, as well as the importance of regular eye fundus examination in these patients.

【 授权许可】

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