Sol-gel as methodology to obtain bioactive materials

Anais da Academia Brasileira de Ciências

Thiago J. Ribeiro¹  Omar J. De Lima¹  Emerson H. Faria¹  Lucas A. Rocha¹  Paulo S. Calefi¹  Katia J. Ciuffi¹  Eduardo J. Nassar¹ 

关键词: biomateriais;    bioativo;    SBF;    metodologia sol­gel;   

DOI  :  10.1590/0001-37652014106012

来源: SciELO

【 摘 要 】

We employed the sol­gel methodology to obtain a silica matrix modified with calcium and phosphate ions. We prepared the matrix by hydrolysis and condensation of the precursors triethyl phosphate, calcium nitrate, and tetraethylorthosilicate, which were the sources of phosphate, calcium, and silicon, respectively. We dried and heat­treated the samples at 110 or 900°C and placed them in simulated body fluid (SBF) for three days. We conducted scanning electron microscopy, X­ray diffraction, and infrared spectroscopy analyses, which evidenced that the sample treated at 110°C contained calcium phosphate silicate and hydroxyapatite before and after contact with SBF, respectively. The sample treated at 900°C exhibited a hydroxyapatite phase before and after contact with SBF, but the crystalline phase was more evident after the contact. In conclusion, the sol­gel methodology provided bioactive samples for bone regeneration.

【 授权许可】

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