Chagas disease in prehistory

Anais da Academia Brasileira de Ciências

Luiz F. Ferreira²  Ana M. Jansen¹  Adauto Araújo² 

[1] ,Fundação Oswaldo Cruz Escola Nacional de Saúde Pública Sergio Arouca Laboratório de PaleoparasitologiaRio de Janeiro RJ ,Brasil

关键词: ancient DNA;    Chagas disease;    mummies;    paleoepideiology;    paleoparasitology;    Trypanosoma cruzi;    ADN antigo;    doença de Chagas;    múmias;    paleoepidemiologia;    paleoparasitologia;    Trypanosoma cruzi;   

DOI  :  10.1590/S0001-37652011005000013

来源: SciELO

【 摘 要 】

The classical hypothesis proposes that Chagas disease has been originated in the Andean region among prehistoric people when they started domesticating animals, changing to sedentary habits, and adopting agriculture. These changes in their way of life happened nearly 6,000 years ago. However, paleoparasitological data based on molecular tools showed that Trypanosoma cruzi infection and Chagas disease were commonly found both in South and North American prehistoric populations long before that time, suggesting that Chagas disease may be as old as the human presence in the American continent. The study of the origin and dispersion of Trypanosoma cruzi infection among prehistoric human populations may help in the comprehension of the clinical and epidemiological questions on Chagas disease that still remain unanswered.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License