Paradoxical sleep deprivation: neurochemical, hormonal and behavioral alterations. Evidence from 30 years of research

Anais da Academia Brasileira de Ciências

Sergio Tufik¹  Monica L. Andersen¹  Lia R. A. Bittencourt¹  Marco T. De Mello¹ 

[1] ,Universidade Federal de São Paulo Escola Paulista de Medicina Departamento de PsicobiologiaSão Paulo SP ,Brasil

关键词: sleep;    sleep deprivation;    rebound;    dopamine;    erection;    corticosterone;    memory;    sono;    privação de sono;    rebote;    dopamina;    ereção;    corticosterona;    memória;   

DOI  :  10.1590/S0001-37652009000300016

来源: SciELO

【 摘 要 】

Sleep comprises approximately one-third of a person's lifetime, but its impact on health and medical conditions remains partially unrecognized. The prevalence of sleep disorders is increasing in modern societies, with significant repercussions on people's well-being. This article reviews past and current literature on the paradoxical sleep deprivation method as well as data on its consequences to animals, ranging from behavioral changes to alterations in the gene expression. More specifically, we highlight relevant experimental studies and our group's contribution over the last three decades.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License