Anthelmintic acetogenin from Annona squamosa L. Seeds

Anais da Academia Brasileira de Ciências

Marta M.c. Souza²  Claudia M.l. Bevilaqua²  Selene M. Morais¹  Cícero T.c. Costa²  Ana R.a. Silva¹  Raimundo Braz-filho¹ 

[1] ,Universidade Estadual do Ceará Laboratório de Doenças Parasitárias

关键词: Haemonchus contortus;    nematodes;    Annonacea;    phytotherapy;    Haemonchus contortus;    nematódeos;    anonácea;    fitoterapia;   

DOI  :  10.1590/S0001-37652008000200005

来源: SciELO

【 摘 要 】

Annona squamosa seeds extracts showed anthelmintic activity against Haemonchus contortus, the main nematode of sheep and goat in Northeastern Brazil. A compound 1 was isolated from ethyl acetate extract and inhibited the egg hatching of H. contortus at 25 mg ml-1. The structure of 1 was determined as a C37 trihydroxy adjacent bistetrahydrofuran acetogenin based on spectroscopic analysis.

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