Follicular dendritic cell sarcoma: report of two cases and literature review

Jornal Brasileiro de Patologia e Medicina Laboratorial

Francisca E. M. M. Lima¹  Iago F. Jorge¹  Jacques Kauffman¹  Gunter Gerson¹  Maria Do Patrocínio F. G. Beco¹  Juliana M. Cavalcante¹  Carlos Gustavo Hirth¹  Raimundo N. L. Neto¹ 

关键词: follicular dendritic cell;    dendritic cell neoplasm;    follicular dendritic cell sarcoma;    pathology;    células dendríticas foliculares;    neoplasias de células dendríticas;    sarcoma de células dendríticas foliculares;    patologia;   

DOI  :  10.5935/1676-2444.20150043

来源: SciELO

【 摘 要 】

ABSTRACTFollicular dendritic cell sarcoma is a rare neoplasm, first described in 1986 by Monda. Case 1: A female patient, 50-year-old performed abdominal computed tomography scan that detected a tumor lesion of 8.0 cm in the mesentery. She underwent resection of the lesion. Microscopic examination revealed epithelioid neoplasm, interspersed with lymphocytes, and positive immunohistochemical staining for CD21 and CD35. The patient underwent adjuvant chemotherapy. Case 2: A male patient, 21-year-old presented right-sided neck mass measuring 7.0 cm. The biopsy revealed proliferation of spindle cells, interspersed with inflammatory infiltrate and storiform arrangement, and positive immunohistochemical staining for CD21 and CD23. The patient underwent neoadjuvant radiotherapy and surgical resection.

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