Renal mixed epithelial and stromal tumor: case report

Jornal Brasileiro de Patologia e Medicina Laboratorial

Karla Lais Pêgas¹  Eduardo Cambruzzi¹  Roque D. Furian¹  Antônio A. Hartmann¹  Suzana Elisabeth Lamonatto¹  Júlia M. Zanatta¹  Kárita Guimarães¹  Elizete Keitel¹  Giovani Thomaz Pioner¹ 

关键词: kidney;    neoplasias;    mixed epithelial and stromal tumor;    pathology;    immunohistochemistry;    rim;    neoplasias;    tumor misto epitelial e estromal;    patologia;    imuno-histoquímica;   

DOI  :  10.5935/1676-2444.20150008

来源: SciELO

【 摘 要 】

Mixed epithelial and stromal tumor (MEST) represents a recently described biphasic kidney neoplasm, which predominantly affects perimenopausal females. The authors report the case of a young male patient with a MEST exhibiting positivity for estrogen and progesterone receptors. Computed tomography/magnetic resonance imaging (CT/MRI) showed an expansive lesion affecting the right kidney. Grossly, a solid-cystic tumor was identified, which measured 5.7 × 3.5 × 2.4 cm. On microscopic examination, a biphasic tumor constituted by stromal and epithelial elements, without significant atypias, was identified. The stromal element was composed of spindle cells revealing positive immunoexpression for actin, desmin, vimentin, and estrogen receptors. The epithelial component exhibited a predominantly tubular pattern showing positive immunoreaction for cytokeratins. The diagnosis of MEST was then established.

【 授权许可】

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