Inclusion-body myositis: a difficult diagnosis?

Jornal Brasileiro de Patologia e Medicina Laboratorial

Carolina Da Cunha Correia¹  Maria Clara De Oliveira Magalhães¹  Pedro Lucas De Mendonça Barbosa¹  Eliene Dutra Campos¹  Edmar Zanoteli¹ 

关键词: skeletal muscle;    myositis;    muscular diseases;    biopsy;    muscle weakness.;    músculo esquelético;    miopatia inflamatória;    doenças musculares;    biópsia;    fraqueza muscular;   

DOI  :  10.5935/1676-2444.20140041

来源: SciELO

【 摘 要 】

Sporadic inclusion-body myositis (IBM) is the most common myopathy in individuals over 55 years of age. However, in many cases, the diagnosis is neglected. Its main findings include progressive muscle weakness, normal or low levels of serum creatine kinase, and the absence of a response to immunosuppression. Muscle biopsy shows inflammatory reaction in association with degenerative changes of the muscle fibers. We report a typical case of IBM, in which diagnosis was possible only after three muscle biopsies. The challenges to confirm histological diagnosis and the caution to avoid repeating tests are discussed.

【 授权许可】

CC BY   
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