Idiopathic pulmonary hemorrhage: morphology and differential diagnosis. Case report

Jornal Brasileiro de Patologia e Medicina Laboratorial

Eduardo Cambruzzi²  Karla Lais Pêgas¹  Túlio Vedana¹ 

[1] ,Universidade Luterana do Brasil

关键词: hemosiderosis;    lung diseases;    alveolar macrophages;    pathology;    hemorrhage;    hemossiderose;    doenças pulmonares;    macrófagos alveolares;    patologia;    hemorragia;   

DOI  :  10.1590/S1676-24442013000300010

来源: SciELO

【 摘 要 】

Idiopathic pulmonary hemorrhage (IPH) is a rare cause of alveolar hemorrhage (AH) with unknown etiology that primarily affects children. The process has a variable clinical progression, and its diagnosis is established after excluding all causes of AH. Herein, the authors report a case of IPH in an adult male patient referring cough and hemoptysis. The conventional radiography computed tomography imaging identified zones of consolidation and areas of ground-glass attenuation in the lower lobes and lingula. Forced spirometry, bronchoscopy, and laboratorial tests yielded normal results. Several alveolar hemosiderin-laden macrophages were identified on bronchoalveolar lavage and lung biopsy. Thus, the histopathological findings associated with clinical data were compatible with IPH.

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