Jornal Brasileiro de Patologia e Medicina Laboratorial | |
Primary osteosarcoma of the thyroid gland: report of a rare neoplasm | |
Eduardo Cambruzzi2  João Grigoleti Scholl1  Alberto Salgueiro Molinari1  Karla Lais Pêgas1  | |
[1] ,Universidade Luterana do Brasil | |
关键词: osteosarcoma; thyroid gland; pathology; immunohistochemistry; osteossarcoma; glândula tireoide; patologia; imuno-histoquímica; | |
DOI : 10.1590/S1676-24442013000100011 | |
来源: SciELO | |
【 摘 要 】
Primary mesenchymal tumors of the thyroid gland are extremely rare. The authors report a case of primary thyroid osteosarcoma in a male patient presenting a tumoral mass in the neck. CT scan demonstrated a large tumor in the right thyroid lobe with areas of calcification. The surgical specimen consisted of a hard brown-gray tumor, measuring 13 × 11 × 7.5 cm. Microscopy revealed a high-grade malignant neoplasm composed of polygonal cells of intermediate size, chondroid pattern in some areas and osteoid formation. The process was immunonegative for AE1/AE3, glial fibrillary acidic protein (GFAP), epithelial membrane antigen (EMA), p53 and thyroid transcription factor-1 (TTF-1), and immunopositive for CD99 and S100. Thus the diagnosis of primary osteosarcoma of the thyroid gland was established.
【 授权许可】
CC BY
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
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RO202005130175419ZK.pdf | 123KB | download |