Lymphoplasmacyte-rich meningioma: a case report of a rare neoplasm

Jornal Brasileiro de Patologia e Medicina Laboratorial

Eduardo Cambruzzi²  Thaís Amara Da Costa De Souza¹  Luciano Carvalho Silveira¹  Carlos Fernando Dos Santos Moreira¹ 

[1] ,Universidade Luterana do Brasil

关键词: Pathology;    Immunohistochemistry;    Central nervous system;    Meningioma;    Brain tumors;    Patologia;    Imuno-histoquímica;    Sistema nervoso central;    Meningeoma;    Tumores cerebrais;   

DOI  :  10.1590/S1676-24442012000300012

来源: SciELO

【 摘 要 】

Lymphoplasmacyte-rich meningioma (LPM) is a rare variant of meningioma, which is characterized by massive inflammatory cell infiltration and rare meningothelial elements. The authors report the clinicopathological features of a LPM located at the right parietal convexity in a patient with generalized tonic-clonic seizures and paresthesia in the left arm. The surgical specimen consisted of a gray nodule measuring 3.5 × 3 × 1.8 cm. At microscopy, a few epithelioid cells associated with numerous lymphocytes/plasma cells were identified. Positive immunoexpression for epithelial membrane antigen (EMA) and progesterone receptor was found in the epithelioid cells, and positive staining for CD3, CD5 and CD20 in the inflammatory cells. Thus, the diagnosis of LPM was established.

【 授权许可】

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