Production of peptide antibiotics by Bacillus sp: GU 057 indigenously isolated from saline soil

Brazilian Journal of Microbiology

Adnan Amin²  Muhammad Ayaz Khan²  Malik Ehsanullah²  Uzma Haroon¹  Sheikh Muhammad Farooq Azam¹  Abdul Hameed¹ 

[1] ,Gomal University Gomal Centre of Biochemistry and Biotechnology D.I.Khan,Pakistan

关键词: Peptide antibiotics;    Bacillus species;    screening;    optimization of parameters;   

DOI  :  10.1590/S1517-83822012000400015

来源: SciELO

【 摘 要 】

A total of 112 soil samples were taken from differents areas of district D.I.Khan and Kohat (KPK) Pakistan and screened for production of antibiotics against the Micrococcus luteus and Staphylococcus aureus. Widest zone of inhibition (18mm) was produced by microorganism isolated from saline soil. The strain was later identified as Bacillus GU057 by standard biochemical assays. Maximum activity (18mm inhibition zone) was observed against Staphylococcus aureus after 48 hours of incubation at pH 8 and 4% concentration of glucose. The antibiotic was identified by autobiography as bacitracin. The Bacillus strain GU057 was confirmed as good peptide antibiotic producer and can effectively be indulged as biocontrol agent.

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