2(5H)-Furanone: a prospective strategy for biofouling-control in membrane biofilm bacteria by quorum sensing inhibition

Brazilian Journal of Microbiology

Kannan Ponnusamy¹  Diby Paul¹  Young Sam Kim¹  Ji Hyang Kweon¹ 

[1] ,Konkuk University Department of Environmental Engineering ,Republic of Korea

关键词: Furanone;    biofilm;    water treatment;    quorum sensing;    N-Acyl homoserine lactone;   

DOI  :  10.1590/S1517-83822010000100032

来源: SciELO

【 摘 要 】

Biofouling of membranes demands costly periodic cleaning and membrane replacement. A sustainable and environmentally friendly solution for maintenance is not available and would be of great interest for many purposes including economical. As complex biofilm formation by environmental strains is the major cause of biofouling and biofilm formation in most cases are controlled by N-Acylhomoserine lactone (AHL)mediated Quorum Sensing (QS). An effort was made to understand the appropriateness of 2(5H)-furanone, to use against biofouling of membranes. QS inhibition activity by 2(5H)-furanone was studied using bioindicator strains and known AHLs of different acyl chain lengths. The biofilm inhibition was studied by growth analysis on polystyrene plate of Aeromonas hyrdrophila, an environmental biofilm strain isolated from a bio-fouled reverse osmosis (RO) membrane. Results showed a QS inhibition activity against a wide range of AHLs and also biofilm formation by 2(5H)-furanone, which is believed to act as a potential quorum inhibition agent in a bacterial biofilm community.

【 授权许可】

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