Epidemiology and phospholipase activity of oral Candida spp. among patients with central nervous system diseases before and after dental cleaning procedure

Brazilian Journal of Microbiology

Aurélia Silva Ribeiro¹  Dágma Aparecida Silva¹  Francislene Pereira Silva¹  Gleicy Carla Santos¹  Lívia Maria Soares Campos¹  Lorena Vivien Neves Oliveira¹  Daniel Assis Santos¹ 

[1] ,Universidade Vale do Rio DoceUniversidade Vale do Rio Doce Faculdade de Ciências da Saúde Laboratório de MicrobiologiaGovernador Valadares MG ,Brasil

关键词: Candida spp.;    cerebral palsy;    Down's syndrome;    metal retardation;    phospholipase;   

DOI  :  10.1590/S1517-83822010000100004

来源: SciELO

【 摘 要 】

Patients suffering of diseases that affect central nervous system may be considered more susceptible to the infectious diseases of mouth. Sixty-nine patients suffering of cerebral palsy, Down's syndrome and metal retardation were submitted to saliva examination for the presence of Candida spp. before and after a procedure of dental cleaning. The isolates were submitted to assay for verifying phospholipase production. 55.10% of the patients provided isolation of Candida spp. The frequency of isolation obtained before dental procedure was: C. albicans (83.33%), C. krusei (8.33%) and C. kefyr, C. parapsilosis and C. glabrata (2.78% each). The frequency after the procedure was: C. albicans (68.57%), C. parapsilosis (11.43%), C. krusei and C. kefyr (8.57% each) and Candida glabrata (2.86%). We verified significantly difference (p < 0.01) between populations obtained at the two examinations. Phospholipase production was verified only among C. albicans strains and the proportion of producers was higher when testing isolates obtained after dental cleaning procedure. Studies focused on Candida spp. isolation are useful for better comprehension of the role of these yeasts on the oral flora from patients with cerebral palsy, Down's syndrome and metal retardation.

【 授权许可】

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