Low prevalence of high risk human papillomavirus in normal oral mucosa by hybrid capture 2

Brazilian Journal of Microbiology

Maria Del Refugio González-losa²  Luis Manzano-cabrera²  Florencio Rueda-gordillo¹  Sandra E. Hernández-solís¹  Marylin Puerto-solís² 

[1] ,Autonomous University of Yucatan Regional Research Center Dr. Hideyo Noguchi Virology LaboratoryMerida Yucatan ,México

关键词: Papillomavirus;    hybrid capture 2;    oral mucosa;    squamous cell carcinoma;    high risk;    Papilomavírus;    Captura Híbrida 2;    mucosa oral;    OSCC;    alto risco;   

DOI  :  10.1590/S1517-83822008000100008

来源: SciELO

【 摘 要 】

High risk human papillomavirus (HR-HPV) are recognized as a necessary factor to development cervical cancer. During the last decade many studies have found HR-HPV in oral squamous cell carcinoma (OSCC) and normal oral mucosa, however the association between HR-HPV and OSCC is still uncertain. The aim of the study was to determine DNA HR-HPV in normal oral cavity of healthy adults. A cross-sectional study was performed; samples from 77 patients with normal oral cavity were collected at the Dentistry school, Autonomous University of Yucatan, Merida, Yucatan, México. HR-HPV was detected by hybrid capture 2. One sample out of 77(1.2%) was positive for HR-PVH. It was from a man of 50 years old. HR-HPV is present in low rate among healthy oral mucosa. Hybrid capture 2 could be a good methodology for large epidemiology studies.

【 授权许可】

CC BY-NC   
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