Chronic infection of cystic fibrosis patient airways by a single clone of Burkholderia cepacia: replacement of non-mucoid to mucoid morphotype

Brazilian Journal of Microbiology

Ana Paula D'alincourt Carvalho¹  Grasiella Maria De Carvalho Ventura¹  Tânia Wrobel Folescu²  Renato Farme D'amoed²  Laurinda Higa²  Lucia Martins Teixeira²  Vânia Lúcia Carreira Merquior¹  Elizabeth De Andrade Marques¹ 

[1] ,Universidade do Estado do Rio de Janeiro Faculdade de Ciências Médicas Rio de Janeiro RJ ,Brasil

关键词: Cystic Fibrosis;    Burkholderia cepacia complex;    PFGE;    RAPD-PCR;    Fibrose Cística;    complexo Burkholderia cepacia;    PFGE;    RAPD-PCR;   

DOI  :  10.1590/S1517-83822003000500014

来源: SciELO

【 摘 要 】

Mucoid Burkholderia cepacia morphotype emerged within a nine year follow-up of a cystic fibrosis patient. Clinical data suggested a linkage between the mucoid phenotype isolation and the deterioration of the patient's condition. Despite of the phenotypic variation, molecular typing showed that the patient was chronically infected with B. cepacia complex isolates belonging to a same genetic clone.

【 授权许可】

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