Sensitivity of AMPLICOR MTB on direct detection of Mycobacterium tuberculosis in smear-negative specimens from outpatients in Rio de Janeiro

Brazilian Journal of Microbiology

Luciano Dos Anjos Filho²  Walter M.r. Oelemann¹  Clara E.n. Barreto¹  Afranio Lineu Kritski²  Leila De Souza Fonseca¹ 

[1] ,Universidade Federal do Rio de Janeiro Hospital Universitário Clementino Fraga Filho Rio de Janeiro RJ ,Brasil

关键词: tuberculosis;    AMPLICOR MTB;    smear-negative specimens;    tuberculose;    AMPLICOR MTB;    espécimes baciloscopia negativa;   

DOI  :  10.1590/S1517-83822002000200013

来源: SciELO

【 摘 要 】

We evaluated the performance of the AMPLICOR MTB assay for detection of M. tuberculosis in clinical specimens obtained from 98 smear-negative tuberculous patients (43 with positive and 55 with negative culture results). The sensitivity of the AMPLICOR MTB was 44.9% (44/98) and that of culture was 43.8% (43/98). No significant difference was observed between the results obtained by AMPLICOR MTB and by culture. We conclude that amplification assays could be used for testing smear-negative specimens because a rapid diagnosis will benefit those patients.

【 授权许可】

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