A suitable procedure to choose antimicrobials as controlling agents in fermentations performed by bacteria

Brazilian Journal of Microbiology

Romulo C. Oliveira²  José G.c. Gomez²  Bayardo B. Torres¹  Celso L. Bueno Netto²  Luiziana F. Da Silva² 

[1] ,Instituto de Pesquisas Tecnológicas do Estado de São Paulo S.A.São Paulo SP ,Brasil

关键词: antimicrobial susceptibility;    MIC;    PHB;    Alcaligenes eutrophus;    Ralstonia eutropha;    sensibilidade a antimicrobianos;    MIC;    PHB;    Alcaligenes eutrophus;    Ralstonia eutropha;   

DOI  :  10.1590/S1517-83822000000200004

来源: SciELO

【 摘 要 】

This work evaluated the influence of nitrofurantoin, erythromycin and streptomycin at 50, 25 and 12,5% of the minimal inhibitory concentration (MIC) on maximum specific growth rate (µmax) and specific polymer accumulation rate (µPHB) of Alcaligenes eutrophus, considered resistant to those antimicrobials. Nitrofurantoin strongly affected µmax even at 50% MIC. Streptomycin moderately affected µmax only at 50%MIC. Nitrofurantoin showed the most harmful effect on µPHB when 50% MIC was applied and erythromycin was not harmful.

【 授权许可】

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