Brazilian Archives of Biology and Technology | |
TT virus in peripheral blood cells from patients with human papillomavirus (HPV): investigating association with cervical carcinoma | |
Patrícia Sayuri Suzuki2  Karen Brajão De Oliveira2  Ana Cristina Do Amaral Herrera1  Sueli Donizete Borelli1  Roberta Losi Guembarovski2  Carlos Eduardo Coral De Oliveira2  Julie Massayo Maeda Oda2  Patricia Midori Murobushi Ozawa2  Maria Angelica Ehara Watanabe2  | |
[1] ,Universidade Estadual de Londrina Centro de Ciências Biológicas Departamento de Ciências PatológicasLondrina PR ,Brasil | |
关键词: TTV DNA; HPV; cervical cancer; | |
DOI : 10.1590/S1516-89132013005000017 | |
来源: SciELO | |
【 摘 要 】
Torque Teno Virus (TTV) presence was investigated in peripheral blood of 117 brazilian women by nested polymerase chain reaction. TTV DNA was observed in 18.6% of healthy donors and in 24.32% Human Papillomavirus (HPV) patients. TTV presence was also investigated in the HPV positive group for comparison between the cervical cancer and noncancerous patients. TTV DNA prevalence was significantly higher among the HPV positive patients with cervical cancer (57.14%) than in HPV noncancerous patients (16.67%). Thus, the presence of TTV infection could be a risk factor for cancer development in the patients presenting HPV-TTV coinfection. Further studies are required to clarify the TTV influence in HPV pathogenesis.
【 授权许可】
CC BY-NC
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
【 预 览 】
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RO202005130166715ZK.pdf | 71KB | download |