Effect of ractopamine on lipid metabolism in vivo - a systematic review

Brazilian Archives of Biology and Technology

Matheus Soares Da Silva Ferreira²  Cesar Augusto Pospissil Garbossa¹  Guilherme Oberlender¹  Luciano José Pereira²  Márcio Gilberto Zangeronimo²  Raimundo Vicente De Sousa²  Vinícius De Souza Cantarelli¹ 

[1] ,Universidade Federal de Lavras Departamento de Medicina Veterinária Lavras MG ,Brasil

关键词: β-adrenergic agonist;    Lipogenesis;    Lipolysis;   

DOI  :  10.1590/S1516-89132013000100005

来源: SciELO

【 摘 要 】

The aim of this article was to evaluate the in vivo mechanism of action through which ractopamine reduces the amount of adipose tissue in carcass of animals fed diets supplemented with this drug. Literature search was carried out, using the keywords Ractopamine, lipogenesis, lipolysis, fatty acid and adipose tissue. The scoring system was designed for the adequacy of the methodology. A total of eight papers were found - all published in the English language. The determination of lipolysis and lipogenesis was carried out using different methods - from the quantification of non-esterified fatty acids in the blood to molecular analyses of adipose tissue. The review analysis suggested that, at least in the pigs, the use of this drug reduced lipid deposition in the carcass due to a greater inhibition of lipogenesis than an increase in lipolysis.

【 授权许可】

CC BY-NC   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License