Cladia aggregata (lichen) from Brazilian northeast: chemical characterization and antimicrobial activity

Brazilian Archives of Biology and Technology

Mônica Cristina Barroso Martins¹  Marcio James Gonçalves De Lima¹  Flávia Pereira Silva¹  Eulália Azevedo-ximenes¹  Nicácio Henrique Da Silva²  Eugênia Cristina Pereira¹ 

[1] ,Universidade Federal de Pernambuco Centro de Ciências Biológicas Departamento de BioquímicaRecife PE ,Brasil

关键词: Cladia aggregata;    barbatic acid;    antimicrobial activity;   

DOI  :  10.1590/S1516-89132010000100015

来源: SciELO

【 摘 要 】

The chemical composition and antimicrobial activity of the Cladia aggregata (Sw.) Nyl. were evaluated. Barbatic acid, depside obtained from C. aggregata, was spectroscopically analyzed and tested, as well as organic extracts. The extracts and purified substance were tested against four Staphylococcus aureus multi-resistant strains. The structure of barbatic acid was confirmed through NMR (¹H; 13C) and elemental ® analysis. Biochromatographic assays showed action of this compound, along with other substances contained in organic extracts, suggesting a synergic action, MIC assays placed barbatic acid in the same level of inhibition to other studied lichen substances.

【 授权许可】

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