Effect of an aqueous extract of annatto (Bixa orellana) seeds on lipid profile and biochemical markers of renal and hepatic function in hipercholesterolemic rats

Brazilian Archives of Biology and Technology

Heberth De Paula²  Maria Lúcia Pedrosa²  Joamyr Victor Rossoni Júnior²  Fabiano Kenji Haraguchi²  Rinaldo Cardoso Dos Santos¹  Marcelo Eustáquio Silva² 

[1] ,Universidade Federal de Ouro Preto Núcleo de Pesquisas em Biologia Ouro Preto MG ,Brasil

关键词: Annatto;    Bixa orellana;    cholesterol;    rat;    aqueous extract;    lipid profile;   

DOI  :  10.1590/S1516-89132009000600008

来源: SciELO

【 摘 要 】

Annatto extract is a natural food color obtained from the outer coatings of the seeds of the Annatto tree (Bixa orellana L.). This is the first report in the literature that shows the relationship between the aqueous annatto extract and its influence on lipid profile in animals. Male Fisher rats were divided into three groups (n=12): C group, fed standard diet and water; H group, fed high-lipid diet and water and; HU group, with high-lipid diet and aqueous annatto extract for 60 days. The treatment with annatto extract in animals fed with the high-lipid diet lowered the LDL- and total cholesterol and raised the HDL-cholesterol, suggesting a hypocholesterolemic effect. Neither high-fat diet nor aqueous annatto extract had any significant effect on serum levels of albumin or serum activities of transaminases which suggested that no liver injury was induced.

【 授权许可】

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