Effects of Cinnamomum zeylanicum treatment on radiolabeling of blood bonstituents and morphology of red blood cells in Wistar rats

Brazilian Archives of Biology and Technology

Mônica Oliveira Benarroz²  Gabrielle De Souza Rocha¹  Márcia Oliveira Pereira¹  Mauro Geller¹  Adenilson De Souza Da Fonseca²  Giuseppe Antonio Presta¹  Mario Bernardo-filho² 

[1] ,Universidade do Rio de Janeiro Instituto de Biologia Roberto Alcantara Gomes Departamento de Biofísica e BiometriaRio de Janeiro RJ ,Brasil

关键词: blood constituents;    Cinnamomum zeylanicum;    technetium-99m;   

DOI  :  10.1590/S1516-89132008000700023

来源: SciELO

【 摘 要 】

The aim of this study was to evaluate the effect of in vivo treatment with an aqueous cinnamon extract on the labeling of blood constituents with 99mTc and on the morphology of red blood cells from Wistar rats. Animals were treated with cinnamon extract at different doses and for different periods of time. As controls, animals treated with 0.9% NaCl. Labeling of blood constituents with 99mTc was performed. Plasma, blood cells and insoluble fractions were isolated. Radioactivity in each fraction was counted and the percentage of radioactivity (%ATI) was calculated. Also, blood smears were prepared to morphological analysis of red blood cells from. Data showed that in vivo cinnamon extract did not significantly (p>0.05) modify the %ATI of blood constituents and morphology of red blood cells. The results suggest that in vivo aqueous cinnamon could not affect the membrane structures involved in transport of ions or the oxidation state of stannous and pertechnetate ions.

【 授权许可】

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