Imaging and therapy with radionuclide labeled magnetic nanoparticles

Brazilian Archives of Biology and Technology

Perihan Ünak¹ 

[1] ,Ege University Institute of Nuclear Sciences Department of Nuclear ApplicationsBornova Izmir,Turkey

关键词: Magnetite Nanoparticles;    radionuclide;    imaging;    therapy;    targeted drug delivery;    iron oxide;   

DOI  :  10.1590/S1516-89132008000700006

来源: SciELO

【 摘 要 】

Magnetic nanoparticles offer exciting new opportunities including the improvement of the quality of magnetic resonance imaging (MRI), hyperthermic treatment for malignant cells, site-specific drug delivery and also the recent research interest of manipulating cell membranes. The biological applications of these nanomaterials require these nanoparticles to have high magnetization values, size smaller than 20 nm, narrow particle size distribution and a special surface coating for both avoiding toxicity and allowing the coupling of biomolecules. In this review, we focus on the feasibility of radionuclide labeled magnetic nanoparticles, as drug carriers, and summarize recent advances in this field.

【 授权许可】

CC BY-NC   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License