Biochemical responses in mice experimentally infected with Paracoccidioides brasiliensis and treated with Canova

Brazilian Archives of Biology and Technology

Gisele Takahachi²  Márcia Luzia Ferrarezi Maluf²  Terezinha Inez Estivalet Svidzinski²  Luciene Setsuko Akimoto-günther²  Márcia Rosangela Neves De Oliveira Hübler²  Ciomar Aparecida Bersani-amado¹  Roberto Kenji Nakamura Cuman¹ 

[1] ,Universidade Estadual de Maringá Departamento de Análises Clínicas

关键词: Paracoccidioidomycosis;    biochemical profile;    Canova;    Paracoccidioides brasiliensis;   

DOI  :  10.1590/S1516-89132006000700006

来源: SciELO

【 摘 要 】

The objective of this work was to evaluate biochemical parameters in Paracoccidioides brasiliensis infected mice and the effect of Canova medicine on these parameters. Mice infected with the isolate Paracoccidioides brasiliensis Pb18 and treated with Canova for 17 weeks were used. The biochemical parameters analysed were the levels of aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase and amylase, and the concentration of total proteins, albumin and globulins. The results suggested that the animals that were treated with Canova had less functional alterations in their internal organs.

【 授权许可】

CC BY-NC   
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