Liquid kit for preparation of 188rhenium-etidronate

Brazilian Archives of Biology and Technology

Barbara Marczewski¹  Carla Roberta Dias¹  Vanessa Moraes¹  João Alberto Osso Junior¹ 

[1] ,CNEN IPEN Instituto de Pesquisas Energéticas e NuclearesSão Paulo SP ,Brasil

关键词: Rhenium-188 HEDP;    Liquid Kit;    Radiolabeling;   

DOI  :  10.1590/S1516-89132005000700019

来源: SciELO

【 摘 要 】

The aim of this study was the preparation of a liquid kit for radiolabeling of 188Re-HEDP (hydroxyethylidene diphosphonate). 188Re was obtained from alumina based 188W/188Re generators. This paper reports the efficacy of a cold kit stored for more than two weeks, determined by the dependence of the radiolabeling yields of 188Re-HEDP on the incubation time, reducing agent concentration, the effects of concentration of ligand, the pH of the reaction and the temperature. The cold kits showed a good stability when carrie-free rhenium-188 was added in the reaction mixture.

【 授权许可】

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