Estudos Sobre Leishmaniose: I. Primeiros Casos de Leishmaniose Espontânea Observados em Cobáios

Brazilian Archives of Biology and Technology

Heitor Medina¹ 

[1] ,Instituto de Biologia e Pesquisas Tecnológicas

关键词: Leishmaniasis;    guinea-pig;   

DOI  :  10.1590/S1516-89132001000500003

来源: SciELO

【 摘 要 】

The author describes the first cases of spontaneous leishmaniasis in guinea-pigs, as verified for the first time, in Curitiba, at the Institute of Biology and Technological Research. Studying the inoculability of Paracoccidioide brasiliensis in guinea-pigs, he found animals which presented tumoral lesions in the ears and peritesticular skin. The examination of these tumors, mixed with a small drop of Giemsa's original solution, plus the exam of the rubbings of the same material, coloured by the May-Grunwald Giemsa after fixation by Heidenhein's solution and the histological exams of the cuts in the tumoral lesions revealed the presence of elements which possessed the same morphology and aspect of the LEISHMAN-DONOVANI corpuscles. In the meanwhile, a parasitosis by protozoarians of the Leishmania variety might have been suspected, because large macrophagi could be seen in the histological cuts, all parazitized, identical with those which are found in other cutaneous leishmaniosis.

【 授权许可】

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