Importance of retardation and fatigue/interest domains for the diagnosis of major depressive episode after stroke: a four months prospective study

Revista Brasileira de Psiquiatria

Luisa De Marillac Niro Terroni²  Renério Fráguas²  Mara De Lucia¹  Gisela Tinone¹  Patricia Mattos²  Dan V. Iosifescu¹  Milberto Scaf¹ 

[1] ,Universidade de São Paulo Institute of Psychiatry Clinical HospitalSão Paulo SP ,Brazil

关键词: Stroke;    Depression;    Depressive disorder;    major;    Signs and symptoms;    Clustering;    Acidente cerebral vascular;    Depressão;    Transtorno depressivo maior;    Sinais e sintomas;    Análise por conglomerados;   

DOI  :  10.1590/S1516-44462009000300004

来源: SciELO

【 摘 要 】

OBJECTIVE: Post-stroke major depressive episode is very frequent, but underdiagnosed. Researchers have investigated major depressive episode symptomatology, which may increase its detection. This study was developed to identify the depressive symptoms that better differentiate post-stroke patients with major depressive episode from those without major depressive episode. METHOD: We screened 260 consecutive ischemic stroke patients admitted to the neurology clinic of a university hospital. Seventy-three patients were eligible and prospectively evaluated. We assessed the diagnosis of major depressive episode using the Structured Clinical Interview for DSM-IV and the profile of depressive symptoms using the 31-item version of the Hamilton Depression Rating Scale. For data analysis we used cluster analyses and logistic regression equations. RESULTS: Twenty-one (28.8%) patients had a major depressive episode. The odds ratio of being diagnosed with major depressive episode was 3.86; (95% CI, 1.23-12.04) for an increase of one unit in the cluster composed by the domains of fatigue/interest and retardation, and 2.39 (95% CI, 1.21-4.71) for an increase of one unit in the cluster composed by the domains of cognitive, accessory and anxiety symptoms. The domains of eating/weight and insomnia did not contribute for the major depressive episode diagnosis. CONCLUSION: The domains of retardation and interest/fatigue are the most relevant for the diagnosis of major depressive episode after stroke.

【 授权许可】

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