Analysis of prescription and dispensation of psychotropic medications in two cities in the State of São Paulo, Brazil

Revista Brasileira de Psiquiatria

Ana Regina Noto²  Elisaldo De A Carlini²  Patrícia C Mastroianni¹  Vanete C Alves²  José Carlos F Galduróz²  Wagner Kuroiwa¹  Jussara Csizmar¹  Agrimeron Costa¹  Mariluci De A Faria¹  Sônia Regina Hidalgo¹  Dirce De Assis¹  Solange Aparecida Nappo² 

[1] ,Brazilian Information Center on Psychotropic DrugsSão Paulo SP ,Brazil

关键词: Psychotropic drugs;    Legislation;    drug;    Prescriptions;    drug;    Anti-anxiety agents;    benzodiazepine;    Analgesics;    opioid;    Amphetamines;    Drug and narcotic control;    Health survey;    Pharmacoepidemiology;    Psicotrópicos;    Legislação de medicamentos;    Prescrição de medicamentos;    Agentes ansiolíticos benzodiazepínicos;    Analgésicos opióides;    Anfetaminas;    Controle de medicamentos e entorpecentes;    Levantamentos epidemiológicos;    Farmacoepidemiologia;   

DOI  :  10.1590/S1516-44462002000200006

来源: SciELO

【 摘 要 】

OBJECTIVES: To investigate the prescription and dispensation of psychotropic medications through the analysis of the prescriptions/notices kept at various institutions in two cities in the state of São Paulo. METHODS: The prescriptions kept at drugstores, magistral pharmacies, primary care settings and hospitals were collected and analyzed in collaboration with the Sanitary Vigilance agencies in the year of 1999. The information in the prescriptions/notices were typed and tabulated. RESULTS: A total of 108,215 prescriptions were processed, being 76,954 for benzodiazepines, 26,930 for anorexigenic drugs, 3,540 for opiates and 788 for other drugs. The benzodiazepines most frequently prescribed were: diazepam (31,644), bromazepam (16,911) and clonazepam (7,929). Among the anorexigenic drugs, diethylpropion (14,800) and femproporex (10,942) were the most common. When compared to men, women were given more prescriptions, mainly for anorexigenic drugs: the ratio was 10:1 in the prescriptions for diethylpropion and femproporex. The few magistral pharmacies (n=6) handled even more prescriptions than did the drugstores (n=49). A number of errors and inconsistencies were detected in the prescriptions analyzed. CONCLUSIONS: The results confirm the occurrence of an irrational use of such medications and a series of inadequate practices related to their prescription in Brazil. Therefore, they point out to the need of a comprehensive review of the government's control system of these substances.

【 授权许可】

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