Incidence of chronic obstructive pulmonary disease based on three spirometric diagnostic criteria in Sao Paulo, Brazil: a nine-year follow-up since the PLATINO prevalence study

Sao Paulo Medical Journal

Graciane Laender Moreira¹  Mariana Rodrigues Gazzotti¹  Beatriz Martins Manzano¹  Oliver Nascimento¹  Rogelio Perez-padilla¹  Ana Maria Baptista Menezes¹  José Roberto Jardim¹ 

关键词: Pulmonary disease;    chronic obstructive;    Incidence;    Diagnosis;    Epidemiology;    Spirometry;    Doença pulmonar obstrutiva crônica;    Incidência;    Diagnóstico;    Epidemiologia;    Espirometria;   

DOI  :  10.1590/1516-3180.2015.9620902

来源: SciELO

【 摘 要 】

CONTEXT AND OBJECTIVE: Chronic obstructive pulmonary disease (COPD) is a respiratory disease of high prevalence and socioeconomic impact worldwide. It affects approximately 16% of the population of São Paulo. The incidence of COPD is still unknown in Brazil. The aim of this study was to estimate new cases of COPD in a population-based sample in São Paulo, Brazil, using three different spirometric diagnostic criteria, and to assess the concordance between these criteria.DESIGN AND SETTING: Prospective cohort study, in the city of São Paulo, Brazil.METHODS: A questionnaire was applied and anthropometry and pre and post-bronchodilator spirometry were performed on the same subjects as in the initial PLATINO study (2003) in São Paulo. Data from this follow-up study were added to the original database of the initial phase. Incident COPD cases refer to subjects who developed the disease in accordance with each spirometric criterion during the nine-year follow-up period. The Statistical Package for the Social Sciences, version 17.0 (SPSS Inc., Chicago, IL, USA) was used in the analysis and the significance level was set at P < 0.05.RESULTS: 613 subjects participated in the follow-up. New COPD cases ranged in frequency from 1.4% to 4.0%, depending on the diagnostic criterion used. The concordance between the criteria ranged from 35% to 60%.CONCLUSION: The incidence of COPD after a nine-year follow-up was high, but varied according to the spirometric criterion used. The agreement between the criteria for identifying new cases of the disease ranged from 35% to 60%.

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