Subacute combined spinal cord degeneration and pancytopenia secondary to severe vitamin B12 deficiency

Sao Paulo Medical Journal

José Luis Cabrerizo-garcía²  Mariano Sebastián-royo¹  Nerea Montes¹  Begoña Zalba-etayo¹ 

[1] ,Defense General Hospital Internal Medicine Service Zaragoza,Spain

关键词: Vitamin B 12 deficiency;    Subacute combined degeneration;    Pancytopenia;    Digestive system abnormalities;    Nervous system diseases;    Deficiencia de Vitamina B 12;    Degeneración combinada subaguda;    Pancitopenia;    Anomalías del sistema digestivo;    Enfermedades del sistema nervioso;   

DOI  :  10.1590/S1516-31802012000400010

来源: SciELO

【 摘 要 】

CONTEXT: Decreased vitamin B12 concentration does not usually result in clinical or hematological abnormalities. Subacute combined spinal cord degeneration and pancytopenia are two serious and rarely displayed consequences that appear in severe deficits. CASE REPORT: We present the case of a patient with subacute combined spinal cord degeneration and pancytopenia secondary to severe and sustained vitamin B12 deficiency. Such cases are rare nowadays and have potentially fatal consequences. CONCLUSIONS: Vitamin B12 deficiency should be taken into consideration in the differential diagnosis in cases of blood disorders or severe neurological symptoms. Early diagnosis and treatment can avoid irreversible consequences.

【 授权许可】

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