Sao Paulo Medical Journal | |
Synchronous thyroid and colon metastases from epidermoid carcinoma of the lung: case report | |
Carla Rameri Alexandre Silva De Azevedo2  Loureno Cezana2  Eduardo Sampaio Patrício De Moraes1  Maria Dirley Ferreira De Souza Begnami1  Tadeu Ferreira Paiva Júnior1  Aldo Lourenço Abbade Dettino1  Marcello Ferretti Fanelli1  | |
[1] ,Hospital A. C. Camargo São Paulo ,Brazil | |
关键词: Thyroid gland; Lung neoplasms; Colon; Neoplasm metastasis; Carcinoma; non-small-cell lung; Glândula tireóide; Neoplasias pulmonares; Colo; Metástase neoplásica; Carcinoma pulmonar de células não pequenas; | |
DOI : 10.1590/S1516-31802010000600011 | |
来源: SciELO | |
【 摘 要 】
CONTEXT: Non-small cell lung cancer (NSCLC) progresses to distant metastases in most cases. The most frequent sites for distant metastases are the bones, central nervous system, adrenal glands and liver. Dissemination to the skin, myocardium, thyroid gland and intestine may occur, but is rare. CASE REPORT: We describe a case of squamous cell carcinoma in the lungs, with metastases in the colon and thyroid, in a 66-year-old female patient. The lesion was unresectable and chemotherapy was started. The patient evolved with intestinal subocclusion, and colonoscopy showed the presence of a polyp. Biopsy and immunohistochemical analysis on the polyp showed that it was compatible with squamous cell carcinoma of pulmonary origin. At a follow-up consultation, the patient presented a thyroid nodule. A aspiration biopsy and cellblock immunohistochemistry confirmed the squamous cell carcinoma of pulmonary origin. After third-line chemotherapy, the patient progressed with acute obstructive abdomen due to a retroperitoneal mass. She underwent exploratory laparotomy and died due to surgical complications. Metastases to the thyroid and colon are rarely reported in cases of epidermoid carcinoma of the lungs. Gastrointestinal involvement in pulmonary metastases may affect the stomach, small intestine and colon, and cases of bleeding and perforation have already been reported. Although richly vascularized, the thyroid is an infrequent site for metastases. Such sites reflect poor prognoses for the clinical evolution. We did not find any previous reports in the literature, on lung cancer with metastases concomitantly in the colon and thyroid, in a single patient.
【 授权许可】
CC BY
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
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