期刊论文详细信息
Sao Paulo Medical Journal
Association between osteoporosis and rheumatoid arthritis in women: a cross-sectional study
Karin Sedó Sarkis2  Mariana Barbieri Salvador2  Marcelo Medeiros Pinheiro1  Raissa Gomes Silva1  Cristiano Augusto Zerbini1  Lígia Araújo Martini2 
[1] ,Universidade de São Paulo Faculdade de Saúde Pública Nutrition DepartmentSão Paulo,Brazil
关键词: Rheumatoid arthritis;    Osteoporosis;    Diet;    Body composition;    Physical activity;    Parathyroid hormone;    Artrite reumatóide;    Osteoporose;    Dieta;    Composição corporal;    Atividade física;    Hormônio paratireóideo;   
DOI  :  10.1590/S1516-31802009000400007
来源: SciELO
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【 摘 要 】

CONTEXT AND OBJECTIVES: Osteoporosis has frequently been observed in patients with rheumatoid arthritis. The present study was undertaken in order to evaluate factors associated with osteoporosis among women with rheumatoid arthritis. DESIGN AND SETTING: Cross-sectional study, carried out in a public hospital in São Paulo. METHODS: The participants were 83 women with rheumatoid arthritis (53.7 ± 10.0 years old). Bone mineral density (BMD) and body composition were measured by dual energy X-ray absorptiometry. The patients were divided into three groups according to BMD: group 1, normal BMD (n = 24); group 2, osteopenia (n = 38); and group 3, osteoporosis (n = 21). Tests were performed to compare differences in means and correlations, with adjustments for age, duration of disease and cumulative corticosteroid. The relationships between clinical factors, physical activity score, dietary intake, body composition and biochemical parameters were analyzed using linear regression models. RESULTS: Mean calcium, vitamin D and omega-6 intakes were lower than the recommendations. Associations were found between BMD and age, disease duration, parathyroid hormone concentration and fat intake. The linear regression model showed that being older, with more years of disease and lower weight were negatively correlated with BMD [Total femur = 0.552 + 0.06 (weight) + 0.019 (total physical activity) - 0.05 (age) - 0.003 (disease duration); R² = 48.1; P < 0.001]. CONCLUSION: The present study indicates that nutritional factors and body composition are associated with bone mass in women with rheumatoid arthritis.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License

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