Does the use of paclitaxel or rapamycin-eluting stent decrease further need for coronary-artery bypass grafting when compared with bare-metal stent?

Sao Paulo Medical Journal

Hernani Pinto De Lemos Júnior²  Álvaro Nagib Atallah¹ 

[1],Brazilian Cochrane Center

关键词: Angina pectoris;    Coronary artery bypass;    Percutaneous transluminal coronary angioplasty;    Myocardial revascularization;    Thoracic surgery;    Angina pectoris;    Ponte de artéria coronária;    Angioplastia transluminal percutânea coronária;    Revascularização miocárdica;    Cirurgia cardíaca;   

DOI  :  10.1590/S1516-31802007000400010

来源: SciELO

【 摘 要 】

CONTEXT AND OBJECTIVE: The safety and efficacy of drug-eluting stents reduce the need for surgical revascularization. The objective of the present study was to investigate whether paclitaxel or rapamycin-eluting stent are effective in avoiding the need for coronary-artery bypass grafting. METHODS: This was a systematic review of the literature using the methodology of the Cochrane Collaboration. The type of study considered was controlled randomized trials; the type of intervention was drug-eluting or bare-metal stents; and the main outcome investigated was coronary-artery bypass grafting. RESULTS: The ten studies included in this systematic review did not show any statistically significant difference between the drug-eluting stents and the bare-metal stents with regard to the outcome of coronary-artery bypass grafting (confidence interval: 0.31 to 1.42). CONCLUSION: The surgical revascularization rate was not reduced by the use of drug-eluting stents.

【 授权许可】

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