Cellular angiofibroma of the vulva: case report with clinicopathological and immunohistochemistry study

Sao Paulo Medical Journal

Adilha Misson Rua Micheletti¹  Ana Cristina Araújo Lemos Da Silva¹  Antonio Geraldo Nascimento¹  Cléber Sérgio Da Silva¹  Eddie Fernando Candido Murta¹  Sheila Jorge Adad¹ 

[1] ,Universidade Federal do Triângulo Mineiro Obstetrics and Pathology Discipline of GynecologyUberaba Minas Gerais ,Brazil

关键词: Angiofibroma;    Connective tissue;    Mesoderm;    Neoplasm;    Vulva;    Angiofibroma;    Tecido conjuntivo;    Mesênquima;    Neoplasia;    Vulva;   

DOI  :  10.1590/S1516-31802005000500010

来源: SciELO

【 摘 要 】

CONTEXT: Cellular angiofibroma of the vulva is a rare tumor that was first described in 1997. It occurs in middle-aged women (average age: 47 years), has small size (< 3 cm) and well-circumscribed margins. CASE REPORT: We describe a case in a 51-year-old woman whose preoperative diagnosis was confounded with Bartholin's glandular cyst. The neoplasia was well delimited and made up of three characteristic components: fusiform cells forming small fascicles, numerous blood vessels and adipose tissue interspersed between the fusiform cells. The stroma cells were positive for vimentin and negative for CD34, protein S-100, actin and desmin. The differential diagnoses for this tumor include aggressive angiomyxoma, angiomyofibroblastoma, lipoma of fusiform cells, solitary fibrous tumor, perineurioma and leiomyoma.

【 授权许可】

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