Darier's disease: a new paradigm for genetic studies in psychiatric disorders

Sao Paulo Medical Journal

Quirino Cordeiro Júnior²  Daniela Meshulam Werebe¹  Homero Vallada¹ 

[1],Universidade de São Paulo Department of Psychiatry São Paulo,Brazil

关键词: Darier's disease;    Depression;    Psychiatry;    Genetics;    Doença de Darier;    Depressão;    Psiquiatria;    Genética;   

DOI  :  10.1590/S1516-31802000000600011

来源: SciELO

【 摘 要 】

CONTEXT: One strategy for identifying susceptibility genes for common disorders is to investigate Mendelian diseases, cosegregating with these common disease phenotypes. CASE REPORT: A family with seven members is described, in which three members present Darier's disease and depression. This apparent cosegregation, if true, would support the hypothesis that in some pedigrees, a gene for mood disorder may be located on chromosome 12.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License