Prognosis related to staging systems for chronic lymphocytic leukemia

Sao Paulo Medical Journal

José Roberto De Faria²  José Salvador Rodrigues De Oliveira¹  Rosa Malena Delbone De Faria²  Maria Regina Regis Silva²  Samuel Goihman¹  Miohoko Yamamoto¹  José Kerbauy¹ 

[1] ,Universidade de Alfenas Division of HematologyMinas Gerais ,Brazil

关键词: Chronic Lymphocytic Leukemia;    Prognosis;    Clinical;    Staging;    Leucemia linfocítica crônica;    Prognóstico;    Clínica;    Estadiamento;   

DOI  :  10.1590/S1516-31802000000400002

来源: SciELO

【 摘 要 】

CONTEXT: Chronic lymphocytic leukemia (CLL) is a clonal lymphoproliferative disorder, characterized by B lymphocytic proliferation. CLL is the most frequent adult leukemia in Western countries, accounting for 25 to 30% of all white leukemic patients. OBJECTIVE: To evaluate clinical and staging characteristics in prognosis of chronic lymphocytic leukemia. DESIGN: Evaluation of clinical-staging data. SETTING: Universidade Federal de São Paulo - Escola Paulista de Medicina / Universidade de Alfenas. SAMPLE: 73 patients diagnosed from 1977 to 1994. MAIN MEASUREMENTS: Sex, ethnic origin, age, lymphadenopathy, splenomegaly, hepatomegaly, three or more areas of lymphoid enlargement, hemoglobin (g/dl), lymphocytes/mm³, Platelets/mm³ RESULTS: Mean survival of patients was 76 months, median age was 65 years, ranging from 33 to 87. Forty-four patients (60.3%) were male and 29 (39.7%) female. CONCLUSION: The Binet system determined a better prognosis than Rai.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License