Perioperative frozen section examination in parotid gland tumors

Sao Paulo Medical Journal

Marcos Brasilino De Carvalho²  João Marcos Arantes Soares¹  Abrão Rapoport²  Josias De Andrade Sobrinho²  Antonio Sérgio Fava²  Jossi Ledo Kanda²  Carlos Neutzling Lehn²  Fernando Walder²  Marcelo Benedito Menezes²  Sérgio Luiz Coelho Negri¹ 

[1] ,Heliópolis HospitalSão Paulo,Brazil

关键词: Frozen section;    Head and Neck tumors;    Parotid gland tumors;    Salivary gland tumors;    Exame por congelação;    Neoplasia de glândula salivar;    Carcinoma de parótida;   

DOI  :  10.1590/S1516-31801999000600002

来源: SciELO

【 摘 要 】

CONTEXT: The minimal recommended surgical approach to parotid tumors is partial parotidectomy with resection of the superficial lobe of the gland. Histologic diagnosis prior to surgery is not possible, as incisional biopsies are contraindicated due to the possibility of facial nerve injury or incomplete tumor resection. Thus, the biopsies tend to be perioperative. OBJECTIVE: To compare the results of frozen section examination with the definitive pathological diagnosis. DESIGN: Accuracy study by retrospective analysis. SETTING: Head and Neck Surgery Service of Heliópolis Hospital, São Paulo, Brazil. SAMPLE: 153 cases of parotid gland tumors treated between 1977 and 1994. DIAGNOSTIC TEST: Frozen section and pathological diagnosis. MAIN MEASUREMENTS: Sensibility and specificity of the frozen section examination. RESULTS: Frozen section study diagnosed 19 (12.4%) malignant and 127 (83.7%) benign tumors. Sensitivity of the frozen sections for malignancy was 61.5% (95% CI 54 to 69%) and specificity was 98% (95% CI 94 to 100%), and this result is comparable to the literature. CONCLUSIONS: We consider that frozen section examination for salivary gland tumors is not sufficient on its own for deciding on the best management. Their interpretation must be correlated with clinical and intraoperative findings, in association with the surgeon's experience.

【 授权许可】

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