Spinal cord compression in b-thalassemia: follow-up after radiotherapy

Sao Paulo Medical Journal

Silvana Fahel Da Fonseca¹  Maria Stella Figueiredo¹  Rodolfo Delfini Cançado¹  Fernando Nakandakare¹  Roberto Segreto¹  José Kerbauy¹ 

关键词: Extramedullary hematopoiesis;    Spinal cord compression;    Intermediate b-thalassemia;   

DOI  :  10.1590/S1516-31801998000600009

来源: SciELO

【 摘 要 】

CONTEXT: Spinal cord compression due to extramedullary hematopoiesis is a well-described but rare syndrome encountered in several clinical hematologic disorders, including b-thalassemia.CASE REPORT: We report the case of a patient with intermediateb-thalassemia and crural paraparesis due to spinal cord compression by a paravertebral extramedullary mass. She was successfully treated with low-dose radiotherapy and transfusions. After splenectomy, she was regularly followed up for over four years without transfusion or recurrence of spinal cord compression. DISCUSSION: Extramedullary hematopoiesis should be investigated in patients with hematologic disorders and spinal cord symptoms. The rapid recognition and treatment with radiotherapy can dramatically alleviate symptoms.

【 授权许可】

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