Sao Paulo Medical Journal | |
Congenital papillomas and papillomatoses associated with the Human Papilloma Virus (HPV): report on 5 cases | |
Eliane Pedra Dias1  José Maria Pinto Barcelos1  Maria Evangelina Ferreira Fonseca1  Nédia Gomes Da Silva Basso1  | |
[1] ,UFF Pathology Department | |
关键词: Congenital Papilloma; HPV; Papillomatosis; | |
DOI : 10.1590/S1516-31801995000400007 | |
来源: SciELO | |
【 摘 要 】
The authors present a study of five cases of vulvar congenital papillomas and papillomatoses in stillborns and neonates dead upon birth. The studied material was collected from five necropsies. The histopathological evaluation showed hyperkeratosis, acanthosis, papillomatosis, perinuclear haloes, and nuclear abnormalities. In three of the cases, the electron microscopy identified nuclear and cytoplasmatic viral particles ranging from 40 to 60 nm in size, compatible with HPV. The immunohistochemical study of those lesions showed nuclear and cytoplasmatic positivity. The authors concluded that the presence of viral particles suggestive of HPV added to the immunopositivity indicated the possibility of viral infection.
【 授权许可】
CC BY
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
【 预 览 】
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RO202005130154920ZK.pdf | 1482KB | download |