Characterization and anti-staphylococcal activity of the essential oil from Turnera subulata Sm.

Revista Brasileira de Plantas Medicinais

M.g. Fernandes²  R.a. Gomes²  S.g. Brito-filho²  R.n. Silva-filho²  M.f. Agra²  V.s. Falcão-silva¹  J.p. Siqueira-junior¹  M.a.r. Vieira¹  M.o.m. Marques¹  M.f.v. Souza² 

[1] ,Federal University of ParaíbaJoão Pessoa PB ,Brasil

关键词: Turnera subulata;    GC-MS;    Turneraceae;    essential oils;    antistaphylococcal activity;    Turnera subulata;    CG-EM;    Turneraceae;    óleo essencial;    atividade antiestafilocócica;   

DOI  :  10.1590/1983-084X/13_011

来源: SciELO

【 摘 要 】

The present study is pioneer in analyzing the chemical composition of the essential oil from aerial parts of Turnera subulata Sm. and evaluates their antibacterial activity against a panel of drug-resistant strains of Staphylococcus aureus. The aerial parts were kiln-dried and then powdered in mechanical mill, and was subjected to hydrodistillation in a Clevenger-type apparatus. The components were analyzed using a mass spectrometrycoupled gas chromatography (GC-MS), and the identification of substances was performed by comparison of the mass spectra obtained with the mass spectra of the database of the GC-MS and retention indices . The essential oil was evaluated using the method of broth dilution at concentrations ranging from 3.125µg/mL to 3200µg/mL. It was possible to identify 45 substances (92.1%) of the essential oils, and the major components were trans-caryophyllene (6.7%), citronellol (5.6%), sphatulenol (5.3%), α-cadinol (4.3%), n-tricosano (4.3%), geraniol (4.1%) and trans-geranilacetone (3.7%), n-pentacosano (3.5%), globulol (3.4%), caryophyllene oxide (3.2%). The essential oil of T. subulata Sm. showed effective antibacterial activity for the various strains of S. aureus tested, with the MIC values between 25 µg/mL and 1600 µg/mL. The study of the essential oil of Turnera subulata Sm. showed that it consists of a complex mixture of several classes of compounds having the sesquiterpenes as major constituents followed by monoterpenes, and showed an antibacterial activity significant front the strains tested.

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