Nutritional risk in hospitalized patients: impact of nutritional status on serum prealbumin

Revista de Nutrição

Bulent Saka¹  Gulistan Bahat Ozturk¹  Sami Uzun¹  Nilgun Erten¹  Sema Genc²  Mehmet Akif Karan¹  Cemil Tascioglu¹  Abdulkadir Kaysi¹ 

[1],Istanbul University Istanbul Faculty of Medicine Department of Internal MedicineIstanbul,Turkey

关键词: Malnutrition;    Nutritional status;    Hospitalized patients;    Prealbumin;    Desnutrição;    Estado nutricional;    Pacientes hospitalizados;    Pré-albumina;   

DOI  :  10.1590/S1415-52732011000100009

来源: SciELO

【 摘 要 】

OBJECTIVE: Poor recognition and monitoring of nutritional status is the most important cause of malnutrition in hospitalized patients. The aim of this study was to assess the nutritional status of a group of patients and compare the results with their serum prealbumin levels. METHODS: Ninety-seven patients admitted consecutively to the hospital were enrolled in the study. The risk of malnutrition was assessed according to anthropometric data and the Subjective Global Assessment and Nutrition Risk Screening 2002 tools. The nutritional statuses of the patients were compared with their age, gender, body mass index, medical history, weight loss and routine biochemical analyses, including prealbumin and length of hospital stay. RESULTS: According to the Nutrition Risk Screening 2002, 57% of the patients were malnourished or at risk of malnutrition, correlating well with the Subjective Global Assessment (p<0.001, r=0.700). Multivariate analysis revealed positive correlations between malnutrition and age, weight loss, malignancy and serum C-reative protein (p=0.046, p=0.001, p=0.04 and p=0.002). Nutrition Risk Screening 2002 score ³3 was associated with prolonged length of hospital stay (p=0.001). Serum prealbumin correlated with nutritional status, regardless of the number of chronic diseases and inflammation biomarkers (p=0.01). Serum prealbumin sensitivity, specificity, positive predictive value, negative predictive value and diagnostic value in the assessment of risk of malnutrition were 94%, 32%, 0.67, 0.78 and 69 respectively. After 7 days of nutritional support, the risk of malnutrition decreased by 12% (p<0.001) and serum prealbumin levels increased by 20% (p=0.003). CONCLUSION: Instead of reflecting overall nutritional status, low serum prealbumin may be regarded as a sign of increased risk of malnutrition, requiring further nutritional assessment. It can be used for monitoring patients receiving nutritional support.

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